Natalie Palamides (born January 6, 1990) is an American actress, comedian and writer. She stars as Buttercup in the 2016 Powerpuff Girls series that airs on Cartoon Network. The show was released in April 4, 2016 in the United States. She reprised her role as Buttercup in the Uncle Grandpa episode "Pizza Eve" during the Grampies short. Palamides has played Kathy Murch in the comedy-horror film Freaks of Nature in October 30, 2015.
She won Best Newcomer at the Edinburgh Comedy Awards in 2017.